Our Practice, Providers & Staff
Our Difference
Why Choose Us
We are the largest private non-hospital owned family practice in Spartanburg, South Carolina providing leading patient care for individuals and families since 1974. Our experienced providers and staff, range of onsite services and state of the art facility make the difference.
Our Mission & Beliefs
Family Physicians seeks to honor Jesus Christ as Lord. Our goal is to serve Christ as we serve our patients. Our state of the art building was constructed with patient care in mind. Come and see the difference in our building, employees, services and physicians.
Our Difference
We strive to serve you and your family to make a difference in your health and wellness. As a single-source primary care provider we offer the most comprehensive in-house specialties and services in the Upstate focusing on all aspects of family medicine. Learn more?
Meet Our Team of Providers
We strive to serve you and your family to make a difference in your health and wellness.

Eric Cole, MD
Family Medicine Physician

Ramona R Hrysikos, FNP
Family Nurse Practitioner

Robert J. Karl, MD
Family Medicine Physician

Mark A Knipfer, MD
Family Medicine Physician

Seth Smith, PA-C
Physician Assistant
Our Talented & Passionate Support Staff
Our dedicated and experienced administrative support staff help to provide excellent patient experience. We love to serve our clients!



JOIN OUR FAMILY & BECOME A PATIENT
Online submission for New Patients & Updates for Existing Patients prior to arrival!
We are accepting new Medicare patients.


